Glossary · Treatments

Black cohosh

Definition: Black cohosh (Actaea racemosa) is a botanical supplement widely used for vasomotor symptoms. Evidence for efficacy is mixed; some randomized trials show modest hot flash reduction, others show no benefit over placebo. Liver toxicity has been reported in rare cases.

Detailed definition

Black cohosh is a North American flowering plant whose root has been used for menopausal symptoms for decades. Mechanism is not fully established and may not involve direct estrogen receptor binding. Multiple RCTs have produced mixed results: some show modest reductions in hot flash frequency vs. placebo, others show no benefit. NAMS does not endorse black cohosh as a recommended treatment but acknowledges that some women report benefit. Rare reports of hepatotoxicity have led to label warnings; baseline and monitoring liver function may be reasonable for women using it long-term. Quality of commercial products varies (the supplement market is unregulated), so standardized extracts from reputable manufacturers are preferred when used.

Why it matters in menopause

Black cohosh occupies a "may help, won't reliably hurt" niche for women who prefer supplements over prescriptions and have mild-to-moderate symptoms. For severe vasomotor symptoms, prescription options (HRT, fezolinetant, venlafaxine) have stronger evidence.

Sources

External references: Wikipedia.

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