Glossary · Pharmacology

USP <795>

Also called: USP General Chapter 795.

Definition: USP <795> is the United States Pharmacopeia standard for non-sterile compounding. It defines requirements for facility, equipment, personnel training, ingredient quality, beyond-use dating, and documentation for compounded medications that do not require sterility (e.g., capsules, creams, ointments).

Detailed definition

United States Pharmacopeia chapter <795> establishes minimum standards for non-sterile compounding in pharmacy practice. It covers facility design, equipment cleanliness, personnel training and competency, quality of starting components, water quality, master and compounding records, and beyond-use dating. State boards of pharmacy generally require 503A compounding pharmacies to comply with USP <795>. The chapter was significantly updated in 2022 to tighten requirements for documentation, beyond-use dating, and personnel training.

Why it matters in menopause

For patients receiving compounded HRT, USP <795> compliance by the dispensing pharmacy is a baseline quality marker. It does not equal FDA-approved product testing but is the closest analog in the compounding world.

Sources

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