Prescribed online by US-licensed physicians

Lose weight with GLP-1 care.

Semaglutide and tirzepatide help quiet constant hunger so you feel full sooner and stay satisfied longer. Choose a weekly injection or a needle-free sublingual option, with your physician adjusting the plan as you go.

Physician-guided dosingNo insurance neededDiscreet delivery
ClearedRx semaglutide vial and tirzepatide sublingual bottle on a travertine shelf Physician-reviewed
Your options

Two medications. Your choice of form.

Your physician recommends the medication and starting dose that fit your health history.

ClearedRx compounded semaglutide injection vial
Semaglutide · GLP-1

Semaglutide Injection

A once-weekly GLP-1 injection that helps regulate appetite.

  • Once-weekly injection
  • Dose increased gradually with your physician
  • Compounded by a licensed US pharmacy
ClearedRx compounded semaglutide sublingual liquid bottle
Semaglutide · Needle-free

Semaglutide Sublingual

The same GLP-1 medication as a liquid held under the tongue.

  • No needles
  • Dosing directions from your physician
  • Compounded by a licensed US pharmacy
ClearedRx compounded tirzepatide injection vial
Tirzepatide · GIP + GLP-1

Tirzepatide Injection

A once-weekly injection that acts on two appetite hormones, GIP and GLP-1.

  • Once-weekly injection
  • Dual GIP and GLP-1 action
  • Dose increased gradually with your physician
ClearedRx compounded tirzepatide sublingual liquid bottle
Tirzepatide · Needle-free

Tirzepatide Sublingual

Dual GIP and GLP-1 medication as a liquid held under the tongue.

  • No needles
  • Dual GIP and GLP-1 action
  • Compounded by a licensed US pharmacy

Compounded medications are prepared by state-licensed US pharmacies. They are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness or quality. Prescription required; a licensed physician decides whether treatment is appropriate.

A woman in her fifties smiling at the top of a sunrise hike
Why GLP-1s

Less food noise. More you.

GLP-1 medications work with the hormones that signal fullness, which is why many people describe fewer cravings and less constant thinking about food. Paired with your own nutrition and activity habits, they can make a healthier weight feel reachable.

  • Physician-guided plan built around your health history
  • Message your care team about dosing and side effects
  • Weekly or needle-free options to fit your routine
How it works

From your couch to your door.

No waiting rooms, no insurance forms, and no video call required for most visits.

1Online visit

Answer a few questions

Share your health history and goals online. It takes a few minutes.

A physician reviewing a patient visit on a laptopVisit reviewed
2Physician review

A physician reviews your visit

A US-licensed physician reviews your answers and prescribes only if treatment is right for you.

A woman picking up a plain, unbranded box at her front doorDelivered
3Delivery

Delivered to your door

Filled by a licensed US pharmacy and shipped in plain, discreet packaging.

Verify Approval for www.clearedrx.comLegitScript certifiedIndependently verified as a legitimate online healthcare provider.
Private and secureYour health information is encrypted and handled under HIPAA.
Discreet deliveryPlain, unbranded packaging with nothing on the outside about what's inside.
30-day money-back guaranteeOn your first order. See the policy.

Important safety information

Semaglutide and tirzepatide are prescription medications and are not right for everyone. Your physician will review your full health history before prescribing.

Do not use if you

  • Have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • Are pregnant, planning a pregnancy or breastfeeding
  • Have had a serious allergic reaction to semaglutide, tirzepatide or any of their ingredients

Possible side effects

The most common side effects are nausea, diarrhea, vomiting, constipation, stomach pain and decreased appetite. Serious side effects can include pancreatitis, gallbladder problems, low blood sugar (especially with other diabetes medications), kidney problems and allergic reactions. Seek medical care right away for severe stomach pain, a lump or swelling in the neck, or signs of a serious allergic reaction.

This is not a complete list. Talk to your physician about all of your medications and conditions. Compounded medications are not FDA-approved.

FAQ

Weight loss, answered.

Still wondering about something? Email support@clearedrx.com or call (202) 951-9915.

What is the difference between semaglutide and tirzepatide?

Semaglutide is a GLP-1 receptor agonist. Tirzepatide acts on two receptors, GIP and GLP-1. Both reduce appetite and help you feel full sooner. Your physician recommends one based on your health history and goals.

Injection or sublingual: which should I choose?

Injections are taken once a week with a small needle. Sublingual liquids are held under the tongue and are needle-free. Your physician will explain the dosing for the form you choose.

Who is eligible for GLP-1 treatment?

Eligibility is decided by a licensed physician after your online visit, based on factors like your BMI, weight-related health conditions and medical history. GLP-1 medications are not right for everyone.

Are compounded GLP-1 medications FDA-approved?

No. Compounded semaglutide and tirzepatide are prepared by state-licensed US pharmacies for individual patients. They are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness or quality.

Do I need insurance?

No. ClearedRx is a cash-pay service, and your price is shown before you check out.

Get started

Ready to get started?

Answer a few questions and a US-licensed physician will review your visit.