Detailed definition
MENQOL is a 29-item questionnaire developed by Hilditch and colleagues in 1996 and validated extensively. Items cover four domains: vasomotor (3 items), psychosocial (7), physical (16), and sexual (3). Each item is rated by whether the respondent has experienced the symptom in the prior month, with severity on a 0–6 scale. Domain scores are means of relevant items. MENQOL is the most-used quality-of-life measure in clinical trials of menopausal hormone therapy and non-hormonal alternatives.
Why it matters in menopause
For research purposes, MENQOL is the standard quality-of-life measure. For routine clinical use, the MRS is shorter and equally suitable.