Status
Completed
Phase
N/A
Study type
Observational
Enrollment
675
Sex
All sexes
Ages
Ages 55 Years and up
Primary completion
2015-10
Last update
2025-06-24

What this trial studies

The Ladies ACS study will investigate the relation between age at menopause and severity of coronary artery disease in menopausal women with acute coronary syndromes and clinical indication to coronary angiography.

Conditions in scope

  • Acute Coronary Syndromes
  • Menopause

Interventions

  • Not specified in the public record.

Who can join

All sexes · Ages 55 Years and up

Inclusion criteria

  • Patients \>55 years of age with all of the following characteristics:
  • symptoms suggestive of acute myocardial ischemia within the previous 48 hours.
  • The diagnosis of an ACS must be confirmed by a typical rise and fall in serum troponin levels as defined by the Third Universal Definition of Myocardial Infarction.
  • ECG signs of myocardial ischemia defined as either transient or persistent ST segment elevation or depression \>0.5 mm (but \>1 mm in the case of ST-segment elevation), or persistent and definite T-wave inversion \>1 mm, including the pseudonormalization of a previously negative T-wave, in ≥2 contiguous leads.

Exclusion criteria

  • none

Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.

Where it’s happening

CityState / RegionFacilitySite status
Reggio Emilia Italy Arcispedale Santa Maria Nuova- IRCCS Unknown

Status & timeline

  • Overall status: Completed
  • Study type: Observational
  • Phase: N/A
  • Start date: 2014-04
  • Primary completion: 2015-10
  • Last update posted: 2025-06-24
  • First posted: 2013-11-28

Lead sponsor: Azienda USL Reggio Emilia - IRCCS (Other Gov)

For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.

Outcome measures

Primary outcomes

  • Extent of coronary artery disease at angio corelab (Gensini and SYNTAX score) (1 day)
    The primary study end-point will be the severity of coronary artery disease, as appraised by the Gensini score

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Important. Information from ClinicalTrials.gov as of May 8, 2026. Trial details (status, sites, contacts, eligibility, outcomes) change frequently — always check the official record at https://clinicaltrials.gov/study/NCT01997307 before contacting a site.

ClearedRx is not affiliated with this trial or its sponsor. We index public-domain ClinicalTrials.gov records to help patients find evidence-based context for menopause care decisions. ClearedRx itself is a telehealth menopause/HRT brand — we do not enroll patients in trials.