What this trial studies
Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve hormonal profile of women in menopause.
Conditions in scope
- Infertility, Female
- Anovulatory Infertility
- Menopause
- Amenorrhea
Interventions
- Autologous PRP intra ovarian infusion (Biological) — Autologous PRP intra ovarian infusion
- Autologous PFP intra ovarian infusion (Biological) — Autologous PFP intra ovarian infusion
Who can join
Women only · Ages 45 Years to 55 Years · Accepts healthy volunteers.
Inclusion criteria
- Age between 45-55 years old
- Amenorrhea for at least 12 months
- Discontinuation of any complementary/adjuvant treatment including hormone replacement, acupuncture, and botanotherapy, for at least three months prior to recruitment.
- Willing to comply with study requirements
Exclusion criteria
- Any pathological disorder related to reproductive system anatomy
- Previous POI diagnosis
- Abnormal karyotype
- Endometriosis
- Adenomyosis
- Fibroids and adhesions
- Infections in reproductive system
- Current or previous diagnosis of reproductive system cancer
Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.
Where it’s happening
| City | State / Region | Facility | Site status |
|---|---|---|---|
| Athens | Genesis AC | Recruiting |
Status & timeline
- Overall status: Recruiting
- Study type: Interventional
- Phase: PHASE2, PHASE3
- Start date: 2019-05-21
- Primary completion: 2026-01-30
- Last update posted: 2024-12-27
- First posted: 2019-04-16
Sponsor & contact
Lead sponsor: Genesis Athens Clinic (Other)
Collaborators: National and Kapodistrian University of Athens
For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.
Outcome measures
Primary outcomes
- Restoration of menstrual cycle (Three months)
Menstrual cycle restoration - Serum FSH levels (Follow-up period of three months entailing monthly evaluation)
Serum FSH levels evaluated monthly for three consecutive months.
Related ClearedRx care
If you’re reading this trial because you have menopause symptoms now, you don’t have to wait for a trial to access evidence-based care. ClearedRx prescribes the same FDA-approved and compounded HRT products that have been studied in trials like this one for decades.
Important. Information from ClinicalTrials.gov as of May 8, 2026. Trial details (status, sites, contacts, eligibility, outcomes) change frequently — always check the official record at https://clinicaltrials.gov/study/NCT03916978 before contacting a site.
ClearedRx is not affiliated with this trial or its sponsor. We index public-domain ClinicalTrials.gov records to help patients find evidence-based context for menopause care decisions. ClearedRx itself is a telehealth menopause/HRT brand — we do not enroll patients in trials.