What this trial studies
The objectives are to evaluate whether variations in vaginal and/or urinary and/or fecal microbiome predispose postmenopausal women to recurrent cystitis. This will be explored using comparison of microbiome profiles between those with recurrent UTI compared to age-matched women without recurrent UTI.
Conditions in scope
- Urinary Tract Infections
- Menopause
Interventions
- Not specified in the public record.
Who can join
Women only · Adults (Child, Adult, Older Adult) · Accepts healthy volunteers.
Inclusion criteria
- Menopausal status
- Sterile urine cultures, normal urinalysis, and negative sexually-transmitted PCR urine assay
Exclusion criteria
- Neurogenic bladder condition
- Known immunodeficiencies
- Usage of antibiotics or probiotics within the previous month
- Known renal calculi or anatomic malformations
- \- A prior history of UTIs or other urologic abnormalities.
Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.
Where it’s happening
| City | State / Region | Facility | Site status |
|---|---|---|---|
| Jerusalem | Jerusalem | Hadassah Medical Center | Recruiting |
Status & timeline
- Overall status: Recruiting
- Study type: Observational
- Phase: N/A
- Start date: 2021-08-01
- Primary completion: 2025-12-30
- Last update posted: 2025-03-19
- First posted: 2020-03-12
Sponsor & contact
Lead sponsor: Hadassah Medical Organization (Other)
For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.
Outcome measures
Primary outcomes
- Characterization of the microbiome using molecular methods. (1 year)
Comparison of microbiome profiles between those with rUTI compared to healthy controls.
Related ClearedRx care
If you’re reading this trial because you have menopause symptoms now, you don’t have to wait for a trial to access evidence-based care. ClearedRx prescribes the same FDA-approved and compounded HRT products that have been studied in trials like this one for decades.
Important. Information from ClinicalTrials.gov as of May 8, 2026. Trial details (status, sites, contacts, eligibility, outcomes) change frequently — always check the official record at https://clinicaltrials.gov/study/NCT04305808 before contacting a site.
ClearedRx is not affiliated with this trial or its sponsor. We index public-domain ClinicalTrials.gov records to help patients find evidence-based context for menopause care decisions. ClearedRx itself is a telehealth menopause/HRT brand — we do not enroll patients in trials.