EFFECTS of BEETROOT JUICE INTAKE and PHYSICAL EXERCISE in POSTMENOPAUSAL HYPERTENSIVE WOMEN

What this trial studies

The goal of this clinical trial is to verify the hemodynamic and biomarker responses of aerobic physical exercise and beetroot juice intake in postmenopausal women with hypertension. The main questions it seeks to answer are: Is beetroot juice and aerobic exercise related to better hemodynamic responses in hypertensive postmenopausal women? Is beetroot juice and aerobic exercise related to better oxidative stress profile responses in hypertensive postmenopausal women? The researchers will conduct a parallel clinical study with 10 days of intervention, in which 48 women will be randomized into 3 groups: 1) Aerobic exercise; 2) One shot of beetroot juice intake per day (400mg of NO3-); 3) Control (no intervention).

Conditions in scope

• Hypertensiona
• Menopause

Interventions

• 1 dose of Beetroot juice intake (Dietary Supplement) — The volunteer will ingest 1 dose of beetroot juice containing 400mg of inorganic nitrate for 10 days.
• Exercise (Other) — The volunteer will perform moderate aerobic exercise for 10 consultative days on a cyclergometer.

Who can join

Women only · Ages 45 Years to 65 Years

Inclusion criteria

• Amenorrhea for at least 12 months
• Controlled hypertension
• Suitable for physical exercise
• Present a certificate proving fitness to practice physical exercise

Exclusion criteria

• Decompensated hypertension in stages 2 and 3
• Having a history of stroke or acute myocardial infarction
• Smoker
• Having physical problems or cardiovascular complications that prevent physical exercise
• Having a diagnosis of Diabetes Mellitus
• Using hormone therapy.

Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.

Where it’s happening

Status & timeline

• Overall status: Active, not recruiting
• Study type: Interventional
• Phase: N/A
• Start date: 2024-08-07
• Primary completion: 2025-07
• Last update posted: 2024-09-23
• First posted: 2024-09-19

Sponsor & contact

Lead sponsor: Federal University of Uberlandia (Other)

For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.

Outcome measures

Primary outcomes

• Hemodynamic responses (11 days)
  Volunteers will undergo blood pressure tests at the beginning, in the middle and after the 10 days of intervention. To assess blood pressure (BP), researchers will use the Dyna Mapa + Cardius® device, programmed with measurements to be taken every 20 min. Together with this device, the volunteers filled out a daily record of activities such as sleep, work, food,…

Related ClearedRx care

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