Effect of Muscle Stiffness on Vertebral Fractures in Women Over 60

What this trial studies

This study aims to assess the quality of lumbar and abdominal core muscles through elastography and evaluate its impact on vertebral fracture risk. This tudy's secondary objective is to investigate the relationship between muscle quality, as measured by elastography, and balance and quality of life. The fundamental questions that this study aims to answer are as follows: Does the quality of lumbar and abdominal core muscles, as assessed by elastography, affect the risk of vertebral fractures? Is there a relationship between muscle quality (as measured by elastography) and balance and quality of life in older adults?

Conditions in scope

• Osteoporosis in Post-menopausal Women
• Vertebral Body Fractures
• Balance, Postural

Interventions

• Elastography Measurements (Other) — Elastography Measurements
• Bone Mineral Density Measurement (DEXA) (Other) — Bone Mineral Density Measurement (DEXA)
• Berg balance scale (Other) — Berg balance scale
• Functional reach test (Other) — Functional reach test
• Timed Up and Go Test (Other) — Timed Up and Go Test

Who can join

Women only · Ages 60 Years and up · Accepts healthy volunteers.

Inclusion criteria

• Female, aged ≥ 60 years

Exclusion criteria

• History of lumbar spine surgery
• Cancer
• Spinal infection
• Severe degenerative scoliosis
• Chronic kidney failure
• Liver cirrhosis
• Bilateral hip arthroplasty

Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.

Where it’s happening

Status & timeline

• Overall status: Completed
• Study type: Observational
• Phase: N/A
• Start date: 2024-11-24
• Primary completion: 2025-01-15
• Last update posted: 2025-08-28
• First posted: 2024-11-14

Sponsor & contact

Lead sponsor: Ankara City Hospital Bilkent (Other)

Collaborators: Samsun Education and Research Hospital

For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.

Outcome measures

Primary outcomes

• Elastography Measurements (8 weeks)
  Measurements were performed using a Mindray ultrasound device (Shenzhen Mindray Biomedical Electronics Co., Ltd., Shenzhen, China) with a 15-3 MHz linear probe in Shear Wave Elastography mode. Ultrasound gel was applied between the probe and the skin to enhance contact. The probe was positioned in line with the muscle fibers and perpendicular to the skin, allowing 2D maps of each…

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