What this trial studies
A Randomized, Double-Blind, Placebo-Controlled, Direct-to-Consumer Trial Assessing the Impact of Health and Wellness Products on Hormonal Health and Associated Health Outcomes in Women with Peri-Menopausal Health Issues
Conditions in scope
- Stress
- Menopause
- Fatigue
- Sleep
Interventions
- Radicle Revive Placebo Control Form 1 (Dietary Supplement) — Participants will use their Placebo Control Form 1 as directed for a period of 6 weeks.
- Radicle Revive Active Study Product 1 (Dietary Supplement) — Participants will use their Radicle Revive Active Study Product 1 as directed for a period of 6 weeks.
Who can join
Women only · Ages 40 Years to 105 Years · Accepts healthy volunteers.
Inclusion criteria
- Adults, at least 40 years of age at the time of electronic consent, inclusive of all ethnicities, races, and gender identities
- Assigned sex at birth is female
- Resides in the United States
- Identifies menstrual status as perimenopausal
- Has the opportunity for at least 30% improvement in their primary health outcome
- Indicates having peri-menopausal issues for 3 months or longer
- Expresses a willingness to take a study product and not know the product identity (active or placebo) until the end of the study
Exclusion criteria
- Individuals who report any of the following during screening will be excluded from participation:
- Reports being pregnant or breastfeeding
- Unable to provide a valid US shipping address and mobile phone number
- Reports current enrollment in another clinical trial
- Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day)
- Unable to read and understand English
- Reports a current and/or recent (up to 3 months ago) major illness and/or surgery that poses a known, significant safety risk.
- Reports a diagnosis of cardiac dysfunction, liver or kidney disease that presents a known contraindication and/or a significant safety risk with any of the study product ingredients.
Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.
Where it’s happening
| City | State / Region | Facility | Site status |
|---|---|---|---|
| Del Mar | California | Radicle Science, Inc | Unknown |
Status & timeline
- Overall status: Completed
- Study type: Interventional
- Phase: N/A
- Start date: 2025-08-05
- Primary completion: 2025-11-12
- Last update posted: 2025-12-17
- First posted: 2025-08-12
Sponsor & contact
Lead sponsor: Radicle Science (Industry)
For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.
Outcome measures
Primary outcomes
- Change in Perceived Stress (6 weeks)
Change in perceived stress: Difference between rates of change over time in Perceived Stress score as assessed by NIH Toolbox Perceived Stress Survey (scale 10-50; where the higher scores correspond to worse perceived stress)
Related ClearedRx care
If you’re reading this trial because you have menopause symptoms now, you don’t have to wait for a trial to access evidence-based care. ClearedRx prescribes the same FDA-approved and compounded HRT products that have been studied in trials like this one for decades.
Important. Information from ClinicalTrials.gov as of May 8, 2026. Trial details (status, sites, contacts, eligibility, outcomes) change frequently — always check the official record at https://clinicaltrials.gov/study/NCT07117994 before contacting a site.
ClearedRx is not affiliated with this trial or its sponsor. We index public-domain ClinicalTrials.gov records to help patients find evidence-based context for menopause care decisions. ClearedRx itself is a telehealth menopause/HRT brand — we do not enroll patients in trials.