Menopause Age and Anxiety-Depression

What this trial studies

Menopause is defined as the permanent cessation of menstrual cycles due to ovarian follicle depletion, typically occurring after age 50, and is associated with decreased estrogen levels. Primary ovarian insufficiency (POI) involves early ovarian dysfunction before age 40, with infertility as a key concern. Both menopause and POI may contribute to psychological symptoms, including anxiety and depression, influenced by sociodemographic and health factors. While literature reports anxiety in middle-aged women, data on its association with menopausal timing are limited.

Conditions in scope

• Menopause
• Primary Ovarian Insufficiency (Poi)
• Anxiety
• Depression
• Menopausal Depression

Interventions

• Beck Anxıety Inventory (BAI) (Other) — Beck Anxıety Inventory (BAI) Description: The scale will be self-administered and completed by the patient during the routine outpatient clinic visit.
• State-Trait Anxiety Scale (STAI) 1-2 (Other) — State-Trait Anxiety Scale (STAI) 1-2 Description: The scale will be self-administered and completed by the patient during the routine outpatient clinic visit.

Who can join

Women only · Ages 24 Years and up · Accepts healthy volunteers.

Inclusion criteria

• Healthy women over 24 years of age who visited our hospital for routine outpatient check-ups, had been diagnosed with menopause, and had no history of psychiatric disorders before menopause.

Exclusion criteria

• Cardiovascular diseases including hypertension
• Type 1 or type 2 diabetes mellitus
• Morbid obesity
• Primary adrenal insufficiency
• Uterine fibroids
• Thyroid dysfunctions including Hashimoto thyroiditis and Grave's disease
• Hepatic dysfunctions
• Renal insufficiency

Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.

Where it’s happening

Status & timeline

• Overall status: Completed
• Study type: Observational
• Phase: N/A
• Start date: 2024-12-15
• Primary completion: 2025-08-05
• Last update posted: 2025-12-19
• First posted: 2025-12-19

Sponsor & contact

Lead sponsor: Ankara City Hospital Bilkent (Other)

For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.

Outcome measures

Primary outcomes

• Beck Anxıety Inventory (BAI), Anxiety level (Baseline (single assessment at enrollment during routine clinic visit).)
  Anxiety severity measured by the Beck Anxiety Inventory (BAI) during routine clinic visit.
• State-Trait Anxiety Scale (STAI) 1-2, Anxiety level (Baseline (single assessment at enrollment during routine clinic visit).)
  Anxiety severity measured by the State-Trait Anxiety Inventory (STAI) forms 1 and 2 during routine clinic visit.

Related ClearedRx care

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