What this trial studies
This prospective observational cohort study aims to evaluate the association between menstrual phase (determined by postoperative serum progesterone levels), intraoperative anesthetic consumption, and the incidence and severity of postoperative nausea and vomiting (PONV) in female patients undergoing cholecystectomy. Intraoperative anesthetic requirements will be recorded, and postoperative nausea and vomiting will be assessed using standardized scoring systems.
Conditions in scope
- Menstrual Cycle
Interventions
- Not specified in the public record.
Who can join
Women only · Ages 18 Years to 65 Years
Inclusion criteria
- Female patients aged 18 to 65 years
- American Society of Anesthesiologists (ASA) physical status I-II-III
- Scheduled for elective laparoscopic cholecystectomy under general anesthesia
- Willing and able to provide written informed consent
Exclusion criteria
- Age outside the specified range (younger than 18 or older than 65 years)
- Male patients
- American Society of Anesthesiologists (ASA) physical status ≥ IV
- Severe systemic comorbidities (e.g., significant cardiovascular, hepatic, renal, or pulmonary disease)
- Conversion from laparoscopic to open cholecystectomy
- History of alcohol, drug, or substance abuse
- Visual or hearing impairment interfering with study assessments
- Current hormone replacement therapy
Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.
Where it’s happening
| City | State / Region | Facility | Site status |
|---|---|---|---|
| Ankara | Ankara | Ankara Etlik City Hospital | Recruiting |
Status & timeline
- Overall status: Recruiting
- Study type: Observational
- Phase: N/A
- Start date: 2026-03-07
- Primary completion: 2026-05-27
- Last update posted: 2026-04-30
- First posted: 2026-03-06
Sponsor & contact
Lead sponsor: Ankara Etlik City Hospital (Other Gov)
For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.
Outcome measures
Primary outcomes
- Intraoperative Anesthetic Agent Consumption (From induction of anesthesia to the end of surgery)
Total amount of anesthetic agents administered during surgery, recorded quantitatively (e.g., mg of intravenous agents and/or minimum alveolar concentration-hours of volatile anesthetics).
Related ClearedRx care
If you’re reading this trial because you have menopause symptoms now, you don’t have to wait for a trial to access evidence-based care. ClearedRx prescribes the same FDA-approved and compounded HRT products that have been studied in trials like this one for decades.
Important. Information from ClinicalTrials.gov as of May 8, 2026. Trial details (status, sites, contacts, eligibility, outcomes) change frequently — always check the official record at https://clinicaltrials.gov/study/NCT07456202 before contacting a site.
ClearedRx is not affiliated with this trial or its sponsor. We index public-domain ClinicalTrials.gov records to help patients find evidence-based context for menopause care decisions. ClearedRx itself is a telehealth menopause/HRT brand — we do not enroll patients in trials.