What this trial studies
This study aims to investigate the effectiveness of manual therapy in women with tension-type headache and to compare treatment outcomes between menopausal and premenopausal women. Hormonal changes occurring during menopause may influence pain perception and headache characteristics. Participants diagnosed with tension-type headache will receive manual therapy interventions. Headache intensity, headache-related disability, pressure pain threshold, cervical range of motion, sleep quality, and quality of life will be evaluated before and after treatment using validated assessment tools.
Conditions in scope
- Tension Type Headache
Interventions
- Manuel Therapy (Procedure) — Participants diagnosed with tension-type headache will receive manual therapy interventions including cervical mobilization, soft tissue techniques, and suboccipital muscle relaxation. Treatments will be applied by a physiotherapist during the study period.
Who can join
Women only · Ages 45 Years to 65 Years
Inclusion criteria
- Women aged between 45 and 65 years Diagnosed with tension-type headache Premenopausal or menopausal status HIT-6 score ≥ 49 Willing to participate in the study
Exclusion criteria
- Use of hormonal therapy History of cervical surgery History of neurological disease Pregnancy Inability to understand questionnaires Failure to attend treatment sessions
Eligibility wording paraphrased from the public record. View the full criteria on ClinicalTrials.gov before contacting a site.
Where it’s happening
| City | State / Region | Facility | Site status |
|---|---|---|---|
| Konya | Konya | Necmettin Erbakan Univesity Faculty of Health Sciences | Recruiting |
Status & timeline
- Overall status: Recruiting
- Study type: Interventional
- Phase: N/A
- Start date: 2025-10-01
- Primary completion: 2026-04
- Last update posted: 2026-03-17
- First posted: 2026-03-17
Sponsor & contact
Lead sponsor: Necmettin Erbakan University (Other)
For trial site contact information, use the official record at ClinicalTrials.gov. Contact details change frequently and the public record is the source of truth.
Outcome measures
Primary outcomes
- Pain İntensity (Visual Analog Scale - VAS) (Baseline and after 2 weeks of treatment)
Pain intensity will be assesed using the Visual Analog Scale (VAS). Participants will rate their pain on a 10 cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain) - Headache İmpact (Headache İmpact Test - HİT-6) (Baseline and after 2 weeks of treatment)
Headache-related disability will be evaluted using the Headache İmpact Test (HİT-6). This questionnaire assesses the impact of headaches on daily functioning, social activities and overall quality of life.
Related ClearedRx care
If you’re reading this trial because you have menopause symptoms now, you don’t have to wait for a trial to access evidence-based care. ClearedRx prescribes the same FDA-approved and compounded HRT products that have been studied in trials like this one for decades.
Important. Information from ClinicalTrials.gov as of May 8, 2026. Trial details (status, sites, contacts, eligibility, outcomes) change frequently — always check the official record at https://clinicaltrials.gov/study/NCT07477483 before contacting a site.
ClearedRx is not affiliated with this trial or its sponsor. We index public-domain ClinicalTrials.gov records to help patients find evidence-based context for menopause care decisions. ClearedRx itself is a telehealth menopause/HRT brand — we do not enroll patients in trials.