The ClearedRx editorial library

Articles & research, all in one place.

Evidence-based education on HRT, menopause symptoms, and women's health — reviewed by the ClearedRx Medical Network. Plus 388 indexed clinical trials and 100+ research-cited statistics.

Articles & treatment guides

Long-form articles on HRT safety, menopause symptoms, treatments, and pricing. Clinician-reviewed, updated as the evidence changes.

HRT Safety

Is HRT Safe? The Evidence, Explained

A clear-eyed look at modern HRT safety data — the WHI study reread, current guidelines, and who HRT is and isn't right for.

Treatment Guides

Hot Flashes Treatment Guide: HRT, Fezolinetant, SSRIs & Lifestyle

Every clinically-backed treatment for menopausal hot flashes compared — HRT, fezolinetant (Veozah), SSRIs, gabapentin, oxybutynin, and lifestyle.

HRT Safety

HRT and Breast Cancer: What the 2026 Evidence Actually Shows

A clinician-reviewed look at absolute risk, estrogen-only vs combination, duration, and the breast-cancer-survivor question.

Getting Started

How Long Does HRT Take to Work? A Week-by-Week Timeline

A clinician-reviewed week-by-week timeline of HRT onset — when hot flashes, sleep, mood, libido, and brain fog typically improve.

Symptoms

Menopause Weight Gain: What HRT Actually Does (and Doesn't)

An honest, evidence-based look at menopause weight gain — the body composition shift, what HRT does indirectly, and what lifestyle changes work.

Special Cases

Surgical Menopause and POI: HRT Guidance for Women Under 45

Why HRT is essentially mandatory after oophorectomy or POI under 45 — and how dosing and duration differ from natural-menopause HRT.

Symptoms

Menopause Brain Fog: How Long It Lasts & What Actually Clears It

Why menopause causes brain fog, how long it lasts, and what evidence-based treatments help — including HRT and lifestyle interventions.

Pricing

How Much Does HRT Cost in 2026? Brand vs Compounded vs Telehealth

Side-by-side cost breakdown of brand-name HRT, compounded options, and telehealth — including hidden fees most providers don't disclose.

Treatment Guides

Types of HRT Explained: Patches, Creams, Pills & Rings

Every HRT delivery method explained — pills, patches, creams, gels, and rings — with pros, cons, and who each works best for.

Education

Perimenopause vs. Menopause: Stages, Symptoms & When to Treat

Clear definitions of perimenopause and menopause, the symptoms that distinguish them, and when treatment becomes appropriate.

Symptoms

Progesterone for Sleep: How Oral Progesterone Treats Menopause Insomnia

How progesterone affects sleep architecture during menopause, and why oral micronized progesterone at bedtime is often the missing piece.

Symptoms

Vaginal Dryness After Menopause: Treatments, Safety & What Actually Works

Half of postmenopausal women have GSM. Every treatment compared: OTC moisturizers, vaginal estrogen cream and ring, DHEA, ospemifene.

Pricing

Compounded Vaginal Estrogen Cost Without Insurance

What compounded vaginal estrogen actually costs cash — and why it's often cheaper than the FDA-approved options at retail.

Treatment Guides

Compounded vs FDA-Approved Vaginal Estrogen

Side-by-side comparison of compounded vaginal estrogen and FDA-approved options — efficacy, safety, cost, and prescriber guidance.

Treatment Guides

How Long Until Vaginal Estrogen Cream Works?

Realistic timelines for vaginal estrogen cream onset — what improves in week 1, week 4, and at 12 weeks.

Telehealth

Telehealth That Prescribes Compounded HRT

Which telehealth platforms work with 503A compounding pharmacies — and what to ask before you book.

HRT Safety

Vaginal Estrogen Black-Box Warning: 2026 Update

What the FDA's reconsideration of the vaginal-estrogen black-box warning means for prescribers and patients.